Sentieon - a competitive alternative to bwa/GATK and DRAGEN
The Sentieon DNAseq suite of read mapping and variant calling tools was designed and implemented as a drop-in replacement for established gold standard read alignment and variant calling tools.
Here we present our evaluation of this suite, demonstrating its accuracy and resource usage when used as a replacement for the bwa/GATK variant calling pipeline or as a competitive alternative to the DRAGEN platform available from Illumina.
- Improve read mapping and variant calling
- Remove inefficiencies at the interface between pipeline components
- Better match data inputs with outputs
- Remove costly data clean-up steps for a more streamlined secondary pipeline